3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and ca...

ID: ALA1133999

Journal: Bioorg Med Chem Lett

Title: 3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth.

Authors: Hu Y, Meuillet EJ, Berggren M, Powis G, Kozikowski AP.

Abstract: 3-Modified D-myo-inositol imidazolyl ether lipid phosphates and a carbonate were synthesized and evaluated as inhibitors of P13-K and Akt. These data are presented along with IC50 values for the inhibition of the growth of three cancer cell lines.

CiteXplore: 11206452

DOI: 10.1016/s0960-894x(00)00640-5

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