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ID: ALA1134011

Journal: Bioorg Med Chem Lett

Title: LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family.

Authors: Chiosis G, Rosen N, Sepp-Lorenzino L.

Abstract: Several LY294002-GM heterodimers were synthesized with the intent of modulating their activity in the presence of hsp90 and thereby creating selective inhibitors of PI3K and PI3K-related family.

CiteXplore: 11294389

DOI: 10.1016/s0960-894x(01)00099-3