Document Report Card

Basic Information

ID: ALA1134025

Journal: Bioorg Med Chem Lett

Title: Thiosugars. Part 9: synthesis and biological evaluation of some 4'-thio-L-arabino nucleoside analogues.

Authors: Wirsching J, Voss J, Adiwidjaja G, Balzarini J, De Clercq E.

Abstract: 1-O-Acetyl-2,3,5-tri-O-benzyl-4-thio-L-arabinofuranose (10) was transformed into the corresponding cytidine derivative 9 and the adenosine derivative 12. Both nucleosides, as well as the previously reported uridine and thymidine analogues 2 and 3, were tested for their in vitro antiviral activity.

CiteXplore: 11327586

DOI: 10.1016/s0960-894x(01)00124-x