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ID: ALA1134085

Journal: Bioorg Med Chem Lett

Title: Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1.

Authors: Dhanak D, Christmann LT, Darcy MG, Jurewicz AJ, Keenan RM, Lee J, Sarau HM, Widdowson KL, White JR.

Abstract: The discovery of a series of phenylalanine derived CCR3 antagonists is reported. Parallel, solution-phase library synthesis has been utilized to delineate the structure-activity relationship leading to the synthesis of highly potent, CCR3-selective antagonists.

CiteXplore: 11378373

DOI: 10.1016/s0960-894x(01)00248-7