Document Report Card

Basic Information

ID: ALA1134086

Journal: Bioorg Med Chem Lett

Title: Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2.

Authors: Dhanak D, Christmann LT, Darcy MG, Keenan RM, Knight SD, Lee J, Ridgers LH, Sarau HM, Shah DH, White JR, Zhang L.

Abstract: Highly potent CCR3 antagonists have been developed from a previously reported series of phenylalanine ester-based leads. Solution-phase, parallel synthesis optimization was utilized to identify highly potent, functional CCR3 antagonists.

CiteXplore: 11378374

DOI: 10.1016/s0960-894x(01)00249-9