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ID: ALA1134151

Journal: Bioorg Med Chem Lett

Title: Solution-phase, parallel synthesis and pharmacological evaluation of acylguanidine derivatives as potential sodium channel blockers.

Authors: Padmanabhan S, Lavin RC, Thakker PM, Guo J, Zhang L, Moore D, Perlman ME, Kirk C, Daly D, Burke-Howie KJ, Wolcott T, Chari S, Berlove D, Fischer JB, Holt WF, Durant GJ, McBurney RN.

Abstract: Solution-phase synthesis of various acylguanidine derivatives and the evaluation of a small library of compounds as potential sodium channel blockers are described.

CiteXplore: 11720863

DOI: 10.1016/s0960-894x(01)00644-8