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ID: ALA1134238

Journal: Bioorg Med Chem Lett

Title: Synthesis of metabolically blocked paclitaxel analogues.

Authors: Wittman MD, Altstadt TJ, Fairchild C, Hansel S, Johnston K, Kadow JF, Long BH, Rose WC, Vyas DM, Wu MJ, Zoeckler ME.

Abstract: The stereospecific syntheses of the metabolically blocked 6-alpha-F, Cl, Br paclitaxel, and 6-alpha-F-10-acetyldocetaxel are described and in vitro and in vivo activity is presented.

CiteXplore: 11277525

DOI: 10.1016/s0960-894x(01)00066-x