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ID: ALA1134712
Journal: Bioorg Med Chem Lett
Title: 2-Aryl indole NK1 receptor antagonists: optimisation of indole substitution.
Authors: Cooper LC, Chicchi GG, Dinnell K, Elliott JM, Hollingworth GJ, Kurtz MM, Locker KL, Morrison D, Shaw DE, Tsao KL, Watt AP, Williams AR, Swain CJ.
Abstract: The synthesis and biological evaluation of a series of 2-aryl indoles with high affinity for the human neurokinin-1 (hNK1) receptor are reported, concentrating on optimisation of the indole substitution.
CiteXplore: 11354384