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ID: ALA1134819

Journal: Bioorg Med Chem Lett

Title: Design and synthesis of potent and selective inhibitors of integrin VLA-4.

Authors: Wattanasin S, Weidmann B, Roche D, Myers S, Xing A, Guo Q, Sabio M, von Matt P, Hugo R, Maida S, Lake P, Weetall M.

Abstract: The synthesis and identification of a novel series of inhibitors of integrin VLA-4 are described. Their in vitro activity and selectivity against closely related integrins are also presented.

CiteXplore: 11677134

DOI: 10.1016/s0960-894x(01)00586-8