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ID: ALA1134945

Journal: Bioorg Med Chem Lett

Title: Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands.

Authors: Wu WL, Caplen MA, Domalski MS, Zhang H, Fawzi A, Burnett DA.

Abstract: A series of aminoalkylazetidines has been discovered as novel ORL1 receptor ligands. Structure-activity relationships have been investigated at the azetidine N and the alkyl side chain sites. Several potent and selective analogues have been identified.

CiteXplore: 12372523

DOI: 10.1016/s0960-894x(02)00652-2