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ID: ALA1134960
Journal: Bioorg Med Chem Lett
Title: Benzotrithiole 2-oxide: a new family of thiol-activated DNA-cleaving functionalities.
Authors: Lee AH, Chan AS, Li T.
Abstract: It was demonstrated in our studies that benzotrithiole 2-oxide was capable of causing efficient DNA cleavage in the presence of 2-mercaptoethanol or glutathione and exhibited potent cytotoxic properties against certain cancer cell lines.
CiteXplore: 12392727