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ID: ALA1135006

Journal: Bioorg Med Chem Lett

Title: Synthesis and biological evaluation of novel 2-(1H-imidazol-4-yl)cyclopropane carboxylic acids: key intermediates for H3 histamine receptor ligands.

Authors: Braña MF, Guisado C, Fernando Alguacil L, Garrido E, Pérez-García C, Ruiz-Gayo M.

Abstract: A new synthetic methodology to provide cis-2-(1H-imidazol-4-yl)-cyclopropane carboxylic acids is described. These cyclopropanes are useful for the preparation of novel H(3) receptor agents.

CiteXplore: 12443776

DOI: 10.1016/s0960-894x(02)00793-x