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ID: ALA1135020

Journal: Bioorg Med Chem Lett

Title: 5-Bromo (or chloro)-6-azido-5,6-dihydro-2' -deoxyuridine and -thymidine derivatives with potent antiviral activity.

Authors: Kumar R.

Abstract: Synthesis, antiviral, and cytotoxic activities of 5-bromo (or chloro)-6-azido-5,6-dihydro-2' -deoxyuridine (4,5) and -thymidine (6,7) are reported. Compounds 4 and 5 exhibited a broad spectrum of antiherpes activity against (HSV-1, HSV-2, HCMV, and VZV).

CiteXplore: 11814776

DOI: 10.1016/s0960-894x(01)00735-1