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ID: ALA1135022

Journal: Bioorg Med Chem Lett

Title: Synthesis and evaluation of imidazo[1,5-a]pyrazines as corticotropin releasing hormone receptor ligands.

Authors: Hartz RA, Gilligan PJ, Nanda KK, Tebben AJ, Fitzgerald LW, Miller K.

Abstract: A novel series of imidazo[1,5-a]pyrazines was synthesized and evaluated as corticotropin releasing hormone (CRH) receptor ligands. SAR studies focused primarily on dialkylamino side chain optimization. SAR of the aryl and small alkyl substituents was also explored.

CiteXplore: 11814780

DOI: 10.1016/s0960-894x(01)00741-7