Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers.
Basic Information
ID: ALA1135032
Journal: Bioorg Med Chem Lett
Title: Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers.
Authors: Tok JB, Wong W, Baboolal N.
Abstract: The design and synthesis of synthetically modified cyclic A-site 16S rRNA construct is reported. The binding characteristics of several members of the aminoglycoside antibiotics with this novel class of synthetically modified A-site 16S rRNA constructs were subsequently investigated.
CiteXplore: 11814798
DOI: 10.1016/s0960-894x(01)00760-0
Patent ID: ┄
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