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ID: ALA1135112

Journal: Bioorg Med Chem Lett

Title: Shikonin derivatives: synthesis and inhibition of human telomerase.

Authors: Lu Q, Liu W, Ding J, Cai J, Duan W.

Abstract: We synthesized DL-shikonin, shikonin, alkanin, and their cyclo-derivatives and acyl-derivatives. These compounds have low cytotoxicity, as well as inhibitory activity against the telomerase enzyme, except cyclo-derivatives.

CiteXplore: 11992780

DOI: 10.1016/s0960-894x(02)00158-0