Document Report Card
Basic Information
ID: ALA1135117
Journal: Bioorg Med Chem Lett
Title: Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives.
Authors: Wyatt PG, Allen MJ, Chilcott J, Gardner CJ, Livermore DG, Mordaunt JE, Nerozzi F, Patel M, Perren MJ, Weingarten GG, Shabbir S, Woollard PM, Zhou P.
Abstract: The paper covers continuing efforts to discover novel, potent and selective oxytocin antagonists. Further benzofuran derivatives with potent oxytocin antagonist activity and good pharmacokinetic parameters are reported. Efforts to improve the in vivo activity of the series are described.
CiteXplore: 11992787