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ID: ALA1135131

Journal: Bioorg Med Chem Lett

Title: Nicotinanilides as inhibitors of neutrophil chemotaxis.

Authors: Cutshall NS, Kucera KA, Ursino R, Latham J, Ihle NC.

Abstract: A series of 4-fluoronicotinanilides was synthesized and shown to be novel, potent, and selective inhibitors against GRO-alpha-driven human neutrophil chemotaxis. Compounds of this class may be useful for the treatment of inflammatory, autoimmune, and allergic disorders.

CiteXplore: 12031332

DOI: 10.1016/s0960-894x(02)00188-9