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ID: ALA1135140

Journal: Bioorg Med Chem Lett

Title: Pyridazines. Part 28: 5-alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors.

Authors: Sotelo E, Fraiz N, Yáñez M, Laguna R, Cano E, Brea J, Raviña E.

Abstract: The synthesis and anti-platelet activity of several 5-alkylidene-6-phenyl-3(2H)-pyridazinones are described. The most active compounds are those that contain oxygenated functions (COOR, COMe) on the alkylidene fragment (6a, 6b and 6c).

CiteXplore: 12039565

DOI: 10.1016/s0960-894x(02)00246-9