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ID: ALA1135170
Journal: Bioorg Med Chem Lett
Title: 4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists II.
Authors: Cooper LC, Carlson EJ, Castro JL, Chicchi GG, Dinnell K, Di Salvo J, Elliott JM, Hollingworth GJ, Kurtz MM, Ridgill MP, Rycroft W, Tsao KL, Swain CJ.
Abstract: A series of novel 4,4-disubstituted cyclohexylamines as NK(1) receptor antagonists is described: modifications to the amine moiety retain NK(1) receptor binding affinity whilst disrupting I(Kr) affinity.
CiteXplore: 12067555