Document Report Card
Basic Information
ID: ALA1135198
Journal: Bioorg Med Chem Lett
Title: Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.
Authors: Faghih R, Dwight W, Gentles R, Phelan K, Esbenshade TA, Ireland L, Miller TR, Kang CH, Fox GB, Gopalakrishnan SM, Hancock AA, Bennani YL.
Abstract: SAR studies for novel non-imidazole containing H(3) receptor antagonists with high potency and selectivity for rat H(3) receptors are described. A high throughput screening lead, A-923, was further elaborated in a systematic manner to clarify a pharmacophore for this class of aryloxyalkyl piperazine based compounds.
CiteXplore: 12113835