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ID: ALA1135233
Journal: Bioorg Med Chem Lett
Title: Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.
Authors: Schoenfeld RC, Conova S, Rittschof D, Ganem B.
Abstract: Synthesis and biological evaluation of two naturally-occurring bromotyramines, moloka'iamine 1 and 3,5-dibromo-4-methoxy-beta-phenethylamine 2, together with several analogues, have been completed. Bromotyramine 2 is cytotoxic, and was found to be a potent antifoulant. Analogues 15 and 16 also displayed significant cytotoxic and antifouling activities.
CiteXplore: 11859011