Structural approach of the mechanism of inhibition of alpha-chymotrypsin by coumarins.

Basic Information

ID: ALA1135275

Journal: Bioorg Med Chem Lett

Title: Structural approach of the mechanism of inhibition of alpha-chymotrypsin by coumarins.

Authors: Wouters J, Huygens M, Pochet L, Pirotte B, Durant F, Masereel B.

Abstract: A pharmacophore associated to the inhibiton of alpha-chymotrypsin has been built based on the structural and electronic characterization of a series of coumarin derivatives.

CiteXplore: 11909728

DOI: 10.1016/s0960-894x(02)00073-2

Patent ID: