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ID: ALA1135323

Journal: Bioorg Med Chem Lett

Title: Dihydroquinolines as novel n-NOS inhibitors.

Authors: Jaroch S, Hölscher P, Rehwinkel H, Sülzle D, Burton G, Hillmann M, McDonald FM.

Abstract: Dihydroquinolines have been synthesized and have been shown to be potent n-NOS inhibitors. Selectivity versus e-NOS was increased to approximately 100-fold through appropriate substitution at the benzene ring.

CiteXplore: 12182860

DOI: 10.1016/s0960-894x(02)00481-x