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ID: ALA1135340
Journal: Bioorg Med Chem Lett
Title: Efficient liquid-phase synthesis of 2'-hydroxychalcones.
Authors: Stoyanov EV, Champavier Y, Simon A, Basly JP.
Abstract: The condensation of 2'-hydroxyacetophenone (1) with aromatic aldehydes (2) in a well closed vessel using microwave irradiation or classical heating at 132 degrees C, provides a fast and simple method for the liquid-phase synthesis of 2'-hydroxychalcones without formation of by-products. Antiproliferative activity of these compounds were evaluated using MCF-7 cells.
CiteXplore: 12217354