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ID: ALA1135359

Journal: Bioorg Med Chem Lett

Title: Antifungal sordarins. Synthesis and structure-activity relationships of 3',4'-fused dioxolane and dioxane derivatives.

Authors: Bueno JM, Cuevas JC, Fiandor JM, García-Ochoa S, Gómez de las Heras F.

Abstract: A number of novel 3',4'-fused dioxolane and dioxane sordarin derivatives were synthesised for structure-activity relationship studies. Many of these derivatives exhibit high activity against Candida spp. and Cryptococcus neoformans.

CiteXplore: 11755335

DOI: 10.1016/s0960-894x(01)00730-2