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ID: ALA1135562

Journal: Bioorg Med Chem Lett

Title: Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.

Authors: Marson CM, Rioja AS, Brooke G, Coombes RC, Vigushin DM.

Abstract: Cyclic acid anhydrides possessing a lipid chain have been shown to be a new class of non-peptidic inhibitors of geranylgeranyl protein-transferase type I (GGPTase-I).

CiteXplore: 11755366

DOI: 10.1016/s0960-894x(01)00718-1