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ID: ALA1135864
Journal: Bioorg Med Chem Lett
Title: Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.
Authors: Watterson SH, Liu C, Dhar TG, Gu HH, Pitts WJ, Barrish JC, Fleener CA, Rouleau K, Sherbina NZ, Hollenbaugh DL, Iwanowicz EJ.
Abstract: A series of novel amide-based small molecule inhibitors of inosine monophosphate dehydrogenase (IMPDH) was explored. The synthesis and the structure-activity relationships (SARs) derived from in vitro studies are described.
CiteXplore: 12270168