Document Report Card

ID: ALA1135896

Journal: J Med Chem

Title: Synthesis and notable antimalarial activity of acyclic peroxides, L-(alkyldioxy)-L-(methyldioxy)cyclododecanes.

Authors: Hamada Y, Tokuhara H, Masuyama A, Nojima M, Kim HS, Ono K, Ogura N, Wataya Y.

Abstract: Of several bis(alkyldioxy)alkanes and the related acyclic peroxides prepared in this study, 1,1-bis(methyldioxy)cyclododecane showed the most notable antimalarial activity particularly in vivo (almost a half of that of artemisinin).

CiteXplore: 11882006

DOI: 10.1021/jm010473w