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ID: ALA1136111

Journal: Bioorg Med Chem Lett

Title: Synthesis and biological testing of non-fluorinated analogues of levofloxacin.

Authors: Gray JL, Almstead JI, Gallagher CP, Hu XE, Kim NK, Taylor CJ, Twinem TL, Wallace CD, Ledoussal B.

Abstract: Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.

CiteXplore: 12824037

DOI: 10.1016/s0960-894x(03)00399-8