Document Report Card
Basic Information
ID: ALA1136144
Journal: Bioorg Med Chem Lett
Title: Hit-to-lead studies: the discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists.
Authors: Baxter A, Bennion C, Bent J, Boden K, Brough S, Cooper A, Kinchin E, Kindon N, McInally T, Mortimore M, Roberts B, Unitt J.
Abstract: A Hit-to-Lead optimisation programme was carried out on the high throughput screening hit, the triazolethiol 1, resulting in the discovery of the potent, orally bioavailable triazolethiol CXCR2 receptor antagonist 45.
CiteXplore: 12873480