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ID: ALA1136217

Journal: Bioorg Med Chem Lett

Title: Mapping the kinase domain of Janus Kinase 3.

Authors: Adams C, Aldous DJ, Amendola S, Bamborough P, Bright C, Crowe S, Eastwood P, Fenton G, Foster M, Harrison TK, King S, Lai J, Lawrence C, Letallec JP, McCarthy C, Moorcroft N, Page K, Rao S, Redford J, Sadiq S, Smith K, Souness JE, Thurairatnam S, Vine M, Wyman B.

Abstract: The utilization and impact of parallel synthesis on lead exploration around initial hit oxindole (1) are described. The emergent SAR, analogue design and functional impact will also be detailed.

CiteXplore: 12941344

DOI: 10.1016/s0960-894x(03)00657-7