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ID: ALA1136281
Journal: Bioorg Med Chem Lett
Title: Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents.
Authors: Kamal A, Ramesh G, Ramulu P, Srinivas O, Rehana T, Sheelu G.
Abstract: Chrysene-linked pyrrolobenzodiazepine hybrids have been prepared that possess cytotoxicity in some cancer cell lines. They also exhibit promising DNA-binding affinity and this is supported by molecular modeling studies.
CiteXplore: 14505647