Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells.

Basic Information

ID: ALA1136311

Journal: Bioorg Med Chem Lett

Title: Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells.

Authors: Oh S, Jeong IH, Shin WS, Lee S.

Abstract: Thioacetal artemisinin derivatives, in particular, 10alpha-phenylthiodihydroartemisinins (5), 10beta-benzenesulfonyl-9-epi-dihydroartemisinin (9) and 10alpha-mercaptodihydroartemisinin (11), exhibit good growth inhibition activity against HUVEC proliferation at the concentration level of 1 microM.

CiteXplore: 14552753

DOI: 10.1016/j.bmcl.2003.08.023

Patent ID: