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ID: ALA1136340
Journal: Bioorg Med Chem Lett
Title: Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.
Authors: Borza I, Kolok S, Gere A, Agai-Csongor E, Agai B, Tárkányi G, Horváth C, Barta-Szalai G, Bozó E, Kiss C, Bielik A, Nagy J, Farkas S, Domány G.
Abstract: A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was studied.
CiteXplore: 14552795