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ID: ALA1136351

Journal: Bioorg Med Chem Lett

Title: Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.

Authors: Kamal A, Ramulu P, Srinivas O, Ramesh G.

Abstract: The synthesis of new A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]-benzodiazepine dimers have been described in this report. These dimers exhibit significant DNA-binding ability with moderate anticancer activity.

CiteXplore: 14592483

DOI: 10.1016/j.bmcl.2003.08.071