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ID: ALA1136395

Journal: Bioorg Med Chem Lett

Title: Multidrug resistance reversal activity of key ningalin analogues.

Authors: Soenen DR, Hwang I, Hedrick MP, Boger DL.

Abstract: Key analogue derivatives of the ningalins, potent multidrug resistance (MDR) reversal compounds, were examined resulting in the discovery of a potent MDR reversal agent that hypersensitizes P-gp resistant tumor cell lines to front-line conventional therapeutic agents.

CiteXplore: 12729663

DOI: 10.1016/s0960-894x(03)00294-4