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ID: ALA1136534
Journal: Bioorg Med Chem Lett
Title: Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors.
Authors: Jaroch S, Hölscher P, Rehwinkel H, Sülzle D, Burton G, Hillmann M, McDonald FM.
Abstract: Dihydroquinolines with aminoalkyl side chains have been synthesized and have been shown to be potent n-NOS inhibitors. A marked selectivity versus e-NOS of up to approximately 300-fold was observed, whereas i-NOS was moderately inhibited.
CiteXplore: 12781178