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ID: ALA1136557

Journal: Bioorg Med Chem Lett

Title: 2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs).

Authors: Blizzard TA, Morgan JD, Mosley RT, Birzin ET, Frisch K, Rohrer SP, Hammond ML.

Abstract: A series of 2-phenylspiroindenes was prepared. The most active analogue (2) was found to be comparable in potency to raloxifene (1) as an estrogen receptor ligand.

CiteXplore: 12565955

DOI: 10.1016/s0960-894x(02)00985-x