Biological evaluation and interconversion studies of rotamers of SCH 351125, an orally bioavailable CCR5 antagonist.

Basic Information

ID: ALA1136594

Journal: Bioorg Med Chem Lett

Title: Biological evaluation and interconversion studies of rotamers of SCH 351125, an orally bioavailable CCR5 antagonist.

Authors: Palani A, Shapiro S, Clader JW, Greenlee WJ, Blythin D, Cox K, Wagner NE, Strizki J, Baroudy BM, Dan N.

Abstract: The separation and biological evaluation of rotamers as well as interconversion studies on rotamers of our clinical candidate SCH 351125 are described.

CiteXplore: 12639563

DOI: 10.1016/s0960-894x(02)01062-4

Patent ID: