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ID: ALA1136606
Journal: Bioorg Med Chem Lett
Title: Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors.
Authors: Glunz PW, Douty BD, Decicco CP.
Abstract: A series of bicyclic pyrimidinone-based HCV NS3 protease inhibitors was synthesized via selective C8 position functionalization. Substituted phenylamides and phenylureas were preferred in the S2 binding pocket.
CiteXplore: 12617891