Document Report Card
Basic Information
ID: ALA1136643
Journal: Bioorg Med Chem Lett
Title: Identification of a novel series of selective 5-HT7 receptor antagonists.
Authors: Forbes IT, Cooper DG, Dodds EK, Douglas SE, Gribble AD, Ife RJ, Lightfoot AP, Meeson M, Campbell LP, Coleman T, Riley GJ, Thomas DR.
Abstract: Novel 5-HT(7) receptor antagonists containing the benzocycloheptanone core were identified from high throughput screening. Molecular modelling and SAR studies have converted these intractable hits into a more potent, selective and tractable series, exemplified by compound (25), SB-691673.
CiteXplore: 12643910