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ID: ALA1136681

Journal: Bioorg Med Chem Lett

Title: [3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.

Authors: Lowe JA, Drozda SE, Fisher K, Strick C, Lebel L, Schmidt C, Hiller D, Zandi KS.

Abstract: The synthesis of NPTS, 6, a potent inhibitor of the type 1 glycine transporter (GlyT1) is described, as well as preparation of 6 in optically active and tritiated form for use as a radioligand for affinity displacement assay of GlyT1.

CiteXplore: 12657266

DOI: 10.1016/s0960-894x(03)00126-4