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ID: ALA1136696
Journal: Bioorg Med Chem Lett
Title: Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analogues.
Authors: Sakya SM, Bertinato P, Pratt B, Suarez-Contreras M, Lundy KM, Minich ML, Cheng H, Ziegler CB, Kamicker BJ, Hayashi SF, Santoro SL, George DM, Bertsche CD.
Abstract: Aryl and hetero aryl substituted 3,6-ketals of 15-membered azalide analogues were synthesized and were found to have potent in vitro antibacterial activity against veterinary pathogens, including Staphylococcus aureus and Pasteurella multocida.
CiteXplore: 12657285