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ID: ALA1136705
Journal: Bioorg Med Chem Lett
Title: Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Authors: Schlemminger I, Mole DR, McNeill LA, Dhanda A, Hewitson KS, Tian YM, Ratcliffe PJ, Pugh CW, Schofield CJ.
Abstract: Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.
CiteXplore: 12668010