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ID: ALA1137000

Journal: Bioorg Med Chem Lett

Title: Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes.

Authors: Rajakumar P, Raja R, Selvam S, Rengasamy R, Nagaraj S.

Abstract: Synthesis of novel quinoline based dicationic benzimidazolophanes and imidazolophanes incorporating various spacer units is described. Some of the quinolinophanes 1b, 3a,3b and 4a exhibit good antibacterial activity against most of the human pathogenic bacteria in the tested concentrations as compared to the other cyclophanes as well as the test control, streptomycin.

CiteXplore: 19477639

DOI: 10.1016/j.bmcl.2009.05.019