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ID: ALA1137121

Journal: Bioorg Med Chem Lett

Title: Oxamides as novel NR2B selective NMDA receptor antagonists.

Authors: Barta-Szalai G, Borza I, Bozó E, Kiss C, Agai B, Proszenyák A, Keseru GM, Gere A, Kolok S, Galgóczy K, Horváth C, Farkas S, Domány G.

Abstract: A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.

CiteXplore: 15225705

DOI: 10.1016/j.bmcl.2004.05.053