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ID: ALA1137252
Journal: Bioorg Med Chem Lett
Title: Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors.
Authors: Puerstinger G, Paeshuyse J, Herdewijn P, Rozenski J, De Clercq E, Neyts J.
Abstract: A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC(50)<100nM) and selectivity (SI>1000) against the pestivirus BVDV (bovine viral diarrhea virus).
CiteXplore: 16901692