Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.

Basic Information

ID: ALA1137529

Journal: Bioorg Med Chem Lett

Title: Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.

Authors: Guery S, Floersheim P, Kaupmann K, Froestl W.

Abstract: The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.

CiteXplore: 17884493

DOI: 10.1016/j.bmcl.2007.09.023

Patent ID: ┄

Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets