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ID: ALA1137582
Journal: Bioorg Med Chem Lett
Title: Quinazoline and benzimidazole MCH-1R antagonists.
Authors: Arienzo R, Cramp S, Dyke HJ, Lockey PM, Norman D, Roach AG, Smith P, Wong M, Wren SP.
Abstract: We have modified the previously reported 2-aminoquinoline 1 to provide two novel series of MCH-1R antagonists. Representative compounds from the quinazoline and benzimidazole series have been shown to be potent and selective, with promising in vitro eADME profiles.
CiteXplore: 17178222